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J Diabetes Complications (2013) 27:26873

Conversely, products of IECs can also directly influence the composition of the microbiota

5.4 Acute Renal Failure There have been postmarketing reports of worsening renal function in patients taking sitagliptin with or without metformin, including acute renal failure, sometimes requiring dialysis

Preclinical research from 2025 shows retatrutide reduces tumor engraftment, delays tumor onset, and significantly decreases tumor volume in mouse models